yxeQ

yxeQ
168

cis-aconitate decarboxylase

Locus
BSU_39460
Molecular weight
47.64 kDa
Isoelectric point
5.94
Protein length
445 aaSequenceBlast
Gene length
1338 bpSequenceBlast
Function
metabolite conversion
Product
cis-aconitate decarboxylase
Essential
no
Synonyms
yxeQ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2079 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,055,536  4,056,873
The protein
Catalyzed reaction/ biological activity
cis-aconitate --> itaconate + CO2 PubMed
Protein family
prpD family (with MmgE, according to UniProt)
Structure
7BRA (PDB) PubMed
P54956 (AlphaFold)
Expression and Regulation
Operons
Genes
yxeK-snaB-yxeM-yxeN-yxeO-sndB-yxeQ
Description
PubMed
Regulation
repressed in the presence of cysteine (CymR) PubMed
Regulatory mechanism
CymR: repression, PubMed, in cymR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed
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yxeK→yxeQ

2025-03-31 02:55:29

Bzhu

101

26e7d8a77b7f64e210508bce49d61eed26cdd5aa

11F447FD5833B59A1639842D70685F9A6B369EAF

Biological materials
Mutant
MGNA-B713 (yxeQ::erm), available at the NBRP B. subtilis, Japan
BKE39460 (yxeQ::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ACCTGCTGTCAGCCCTTGTT,  downstream forward: _UP4_TAAGATCAACTCTATTCGGT
BKK39460 (yxeQ::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ACCTGCTGTCAGCCCTTGTT,  downstream forward: _UP4_TAAGATCAACTCTATTCGGT
References
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7DDB283173267AA106DC277787AAAB4F4F9975F4

Page visits: 3054

Time of last update: 2025-04-12 08:54:49

Author of last update: Jstuelk