cydB

cydB
168

cytochrome bd ubiquinol oxidase (subunit II), high affinity terminal oxidase

Locus
BSU_38750
Molecular weight
37.70 kDa
Isoelectric point
9.48
Protein length
338 aaSequenceBlast
Gene length
1017 bpSequenceBlast
Function
respiration
Product
cytochrome bd ubiquinol oxidase (subunit II), high affinity terminal oxidase
Essential
no
Synonyms
cydB, yxkL
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1294 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,976,791 → 3,977,807
The protein
Catalyzed reaction/ biological activity
2 ubiquinol + n H+ + O2 --> 2  ubiquinone + n H+ + 2 H2O (according to UniProt)
Protein family
cytochrome ubiquinol oxidase subunit 2 family (with YthB, according to UniProt)
Cofactors
heme b, heme d (according to UniProt)
Structure
P94365 (AlphaFold)
Localization
cell membrane (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
cydA-cydB-cydC-cydD
Description
PubMed
Regulation
expressed under anaerobic conditions (ResD) PubMed
Expression
expression is heterogeneous PubMed
Regulatory mechanism
CcpA: repression, in ccpA regulon
Rex: repression, PubMed, in rex regulon
ResD: activation, PubMed, in resD regulon
Sigma factors
SigF: sigma factor, PubMed, in sigF regulon
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cydA→cydD

2025-03-17 19:43:41

Jstuelk

121

B656DC522BB35F8FB6BB0C0BBC86CB05C20AB7C7

80895031322ED50D8EABA337924455145A6261DF

Biological materials
Mutant
MGNA-B746 (cydB::erm), available at the NBRP B. subtilis, Japan
BKE38750 (ΔcydB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GATCATGAAGAGATGCCATG,  downstream forward: _UP4_CATAAGGAGCCTATGACTTA
BKK38750 (ΔcydB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_GATCATGAAGAGATGCCATG,  downstream forward: _UP4_CATAAGGAGCCTATGACTTA
References
Reviews
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Original Publications
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E66EAB3C172ED8D1D26C675A7338B8153FB66987

Page visits: 3368

Time of last update: 2025-04-09 12:29:36

Author of last update: Jstuelk