ywhC

ywhC
168

similar to site-2 protease

Locus
BSU_37530
Molecular weight
24.56 kDa
Isoelectric point
9.74
Protein length
Gene length
Function
unknown
Product
unknown
Essential
no
Synonyms
ywhC

Genomic Context

List of homologs in different organisms, belongs to COG1994 (Galperin et al., 2021)

Gene
Coordinates
3,852,718  3,853,377
The protein
Protein family
peptidase M50B family (according to UniProt)
Structure
3B4R (PDB) (from Methanocaldococcus jannaschii, corresponds to aa 15 ... 166, 30% identity) PubMed
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
Description
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ywhCywhD

2024-12-30 17:09:51

Jstuelk

58

053a40dd97d3b22f7bf500d66f352b639e4316e2

37E166A491036925457C4472BBAEE349A3A60249

Biological materials
Mutant
MGNA-A518 (ywhC::erm), available at the NBRP B. subtilis, Japan
BKE37530 (ywhC::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CAAGTGAGATATCCCTCTTT,  downstream forward: _UP4_CCGCTTTTGTAGGAGGTAGA
BKK37530 (ywhC::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CAAGTGAGATATCCCTCTTT,  downstream forward: _UP4_CCGCTTTTGTAGGAGGTAGA
References
Reviews
Harwood CR, Kikuchi YThe ins and outs of Bacillus proteases: activities, functions and commercial significance.FEMS microbiology reviews. 2021 Aug 19; . PMID: 34410368
Original Publications
Feng L, Yan H, Wu Z, Yan N, Wang Z, Jeffrey PD, Shi Y Structure of a site-2 protease family intramembrane metalloprotease. Science (New York, N.Y.). 2007 Dec 07; 318(5856):1608-12. . PMID:18063795

7CBBC3649B7E37AC33A018C23085748AA6CA1121

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Time of last update: 2025-01-17 23:38:50

Author of last update: Jstuelk