ywiE

ywiE
168

minor cardiolipin synthetase, general stress protein, required for protection against paraquat stress

Locus
BSU_37240
Molecular weight
58.08 kDa
Isoelectric point
8.38
Protein length
500 aaSequenceBlast
Gene length
1503 bpSequenceBlast
Function
phospholipiid biosynthesis, protection against paraquat stress
Product
minor cardiolipin synthetase
Essential
no
E.C.
null
Synonyms
ywiE
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1502 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,821,570  3,823,072
The protein
Catalyzed reaction/ biological activity
2 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) --> cardiolipin + glycerol (according to UniProt)
Protein family
phospholipase D family (with YwjE and ClsA, according to UniProt)
Domains
2 PLD phosphodiesterase domains (aa 237-264, aa 413-440) (according to UniProt)
Structure
P45860 (AlphaFold)
Paralogous protein(s)
ClsA, YwjE
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
ywiE-ywjA-ywjB
Description
PubMed
Regulatory mechanism
Fur: repression, PubMed, in fur regulon
Sigma factors
SigB: sigma factor, PubMed, in sigB regulon
Open in new tab

ywiE->ywjB

2025-04-09 13:54:24

Bzhu

70

212b18f4698de19cc17ce4d25e56c42b2e6ee3aa

1388A2364B0BC385CFA90298AFC1348C8DFABFBB

Biological materials
Mutant
MGNA-A553 (ywiE::erm), available at the NBRP B. subtilis, Japan
BKE37240 (ywiE::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCTGATTCTCTCCAATC,  downstream forward: _UP4_TAAGAAAAAAGAAATCTGAT
BKK37240 (ywiE::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCTGATTCTCTCCAATC,  downstream forward: _UP4_TAAGAAAAAAGAAATCTGAT
References
Loading

07752EC6940F43DEBD1E9313A2A195E35EDB9F69

Page visits: 5675

Time of last update: 2025-04-10 19:23:14

Author of last update: Melvin.boenninger