glnK

glnK
168

two-component sensor kinase, regulation of the glsA-glnT operon

Locus
BSU_02440
Molecular weight
44.00 kDa
Isoelectric point
5.73
Protein length
410 aaSequenceBlast
Gene length
1233 bpSequenceBlast
Function
regulation of the glsA-glnT operon
Product
two-component sensor kinase
Essential
no
Synonyms
glnK, ycbA, yzgA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0642 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
265,476 → 266,708
The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of GlnL
ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine (according to UniProt)
Domains
four transmembrane segments
Histidine kinase domain (aa 189-405) (according to UniProt)
Structure
P40758 (AlphaFold)
Modification
autophosphorylation on a His residue
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
glnK-glnL
Description
PubMed
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glnK→glnL

2025-04-10 00:08:07

Jstuelk

89

53ffb3f99cce8c4721a7de587eae3ce84afee383

5FB071BA0D146528DE35BFF31F938BD208BF8C20

Biological materials
Mutant
BKE02440 (ΔglnK::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGAGGGCCAGTATATATC,  downstream forward: _UP4_ATTCAGAAAGGGTGAACCAA
BKK02440 (ΔglnK::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGAGGGCCAGTATATATC,  downstream forward: _UP4_ATTCAGAAAGGGTGAACCAA
References
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C18B886D06879C64B64606371E85A7D4D22DCFAC

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Time of last update: 2025-04-11 00:14:14

Author of last update: Melvin.boenninger