ytcB

ytcB
168

putative UDP-glucose epimerase

Locus
BSU_30870
Molecular weight
34.76 kDa
Isoelectric point
8.87
Protein length
316 aaSequenceBlast
Gene length
951 bpSequenceBlast
Function
unknown
Product
putative UDP-glucose epimerase
Essential
no
Synonyms
ytcB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0451 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,157,008  3,157,958
The protein
Protein family
NAD(P)-dependent epimerase/dehydratase family (according to UniProt)
Structure
1SB8 (PDB) (Pseudomonas aeruginosa UDP-N-acetylglucosamine 4-epimerase, 34% identity) PubMed, 5U4Q (PDB) (from Klebsiella pneumoniae 35% identity)
O34886 (AlphaFold)
Paralogous protein(s)
YfnG, (29,5%)
Expression and Regulation
Operons
Genes
ytcA-ytcB-ytcC
Description
PubMed
Regulation
expressed late during sporulation in the mother cell (SigKC, GerE) PubMed
Regulatory mechanism
GerE: repression, PubMed, in gerE regulon
Sigma factors
SigK: sigma factor, PubMed, in sigK regulon
Open in new tab

ytcA→ytcC

2025-03-17 19:02:52

Jstuelk

72

0fd4b4ec2d5d2a00711b534b6ea0edb15aa22353

7C19F03C64E72EC0930CBFC53B593F1821A2DD28

Biological materials
Mutant
MGNA-A279 (ytcB::erm), available at the NBRP B. subtilis, Japan
BKE30870 (ytcB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CGCTGCTCCTGTGACGAGTA,  downstream forward: _UP4_TCGCTGTATCAGGGGGAATA
BKK30870 (ytcB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CGCTGCTCCTGTGACGAGTA,  downstream forward: _UP4_TCGCTGTATCAGGGGGAATA
References
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A51B5F9F86D2F7B690712B9EC181B1C07B312E02

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Time of last update: 2025-04-24 10:04:23

Author of last update: Jstuelk