aroC

aroC
168

3-dehydroquinate dehydratase

Locus
BSU_23080
Molecular weight
27.98 kDa
Isoelectric point
4.9
Protein length
255 aaSequenceBlast
Gene length
768 bpSequenceBlast
Function
biosynthesis of aromatic amino acids
Product
3-dehydroquinate dehydratase
Essential
no
E.C.
4.2.1.10
Synonyms
aroC
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0710 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,412,706  2,413,473
The protein
Catalyzed reaction/ biological activity
3-dehydroquinate --> 3-dehydroshikimate + H2O (according to UniProt)
Protein family
type-I 3-dehydroquinase family (single member, according to UniProt)
Structure
1GQN (PDB) (from Salmonella typhi, 55% identity, 70% similarity) PubMed
P35146 (AlphaFold)
Expression and Regulation
Operons
Genes
aroC
Description
PubMed
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aroC

2025-02-26 15:23:18

ghost

51

fa31cda766be1fafb8480390ba423d363c16b6f2

67ADDCD79E48CEC7F9522ADCA6C2350B7DC2B0FA

Biological materials
Mutant
BKE23080 (aroC::erm  trpC2) available at BGSC and in Jörg Stülke's lab,  PubMed, upstream reverse: _UP1_CACTCGTCTCAAATCCTTTC,  downstream forward: _UP4_TAGAACAATAAAAAAACTCA
BKK23080 (aroC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACTCGTCTCAAATCCTTTC,  downstream forward: _UP4_TAGAACAATAAAAAAACTCA
References
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Page visits: 2406

Time of last update: 2025-04-23 22:40:53

Author of last update: Melvin.boenninger