kdgR

kdgR
168

transcriptional repressor of the pectin utilization operon (LacI family)

Locus
BSU_22120
Molecular weight
37.70 kDa
Isoelectric point
8.82
Protein length
339 aaSequenceBlast
Gene length
1020 bpSequenceBlast
Function
regulation of galacturonic acid utilization
Product
transcriptional repressor of the pectin utilization operon (LacI family)
Essential
no
Synonyms
kdgR
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1609 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,324,613  2,325,632
The protein
Protein family
LacI family
Domains
HTH lacI-type domain (aa 9-64) (according to UniProt)
Structure
2HSG (PDB) (B. megaterium CcpA, 26% identity) PubMed
P50844 (AlphaFold)
Expression and Regulation
Operons
Genes
kdgR-kdgK-kdgA-kdgT
Description
PubMed
Regulation
induced by galacturonate (KdgR) PubMed
Regulatory mechanism
KdgR: repression, PubMed, in kdgR regulon
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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kdgR→kdgT

2025-03-27 16:20:43

Jstuelk

99

a5bed599599ed10a0553e473cf3c537c32010d6c

3F117D89C62E073C1B4EEA2460C1BBFC9A05A5A3

Biological materials
Mutant
BKE22120 (kdgR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCAAGTGCTCCTGTATC,  downstream forward: _UP4_TAATCCTAGGTGCCCTCAAC
BKK22120 (kdgR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCAAGTGCTCCTGTATC,  downstream forward: _UP4_TAATCCTAGGTGCCCTCAAC
References
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891A32A19D1353BA566FF121BBCA7B986D31D129

Page visits: 4787

Time of last update: 2025-04-14 05:29:42

Author of last update: Melvin.boenninger