tlp

tlp
168

thioredoxin-like protein

Locus
BSU_18030
Molecular weight
9.58 kDa
Isoelectric point
4.44
Protein length
83 aaSequenceBlast
Gene length
252 bpSequenceBlast
Function
unknown
Product
thioredoxin-like protein
Essential
no
Synonyms
tlp
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5863 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,930,447 → 1,930,698
The protein
Protein family
tlp family (single member, according to UniProt)
Structure
Q45060 (AlphaFold)
Localization
spore core (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
sspN-tlp
Description
PubMed
Regulation
expressed during sporulation in the forespore (SigF, SigG) PubMed
Sigma factors
SigF: sigma factor, PubMed, in sigF regulon
SigG: sigma factor, PubMed, in sigG regulon
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sspN→tlp

2025-03-30 23:03:19

ghost

78

8757a4161c7c7017b6527853073d00cd7adc790d

E3663BCFF3D69A8223B9D0560AEF3E5D7F092C1D

Additional information
the mRNA belongs to the 46 most abundant mRNA species in dormant spores PubMed
Biological materials
Mutant
BKE18030 (Δtlp::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCGGATGTACCTCCTAG,  downstream forward: _UP4_TAAAAAACCAGGGAAACCTG
BKK18030 (Δtlp::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCGGATGTACCTCCTAG,  downstream forward: _UP4_TAAAAAACCAGGGAAACCTG
References
Reviews
Galperin MY, Yutin N, Wolf YI, Vera Alvarez R, Koonin EVConservation and Evolution of the Sporulation Gene Set in Diverse Members of the Firmicutes.Journal of bacteriology. 2022 May 31; :e0007922. PMID: 35638784
Original Publications
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Page visits: 2068

Time of last update: 2025-04-10 18:28:51

Author of last update: Jstuelk