uxaC

uxaC
168

glucuronate isomerase (D-glucuronate, D-galacturonate)

Locus
BSU_12300
Molecular weight
54.44 kDa
Isoelectric point
5.17
Protein length
Gene length
Function
hexuronate utilization
Product
glucuronate isomerase (D-glucuronate, D-galacturonate)
Essential
no
E.C.
5.3.1.12
Synonyms
uxaC, yjmA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1904 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,300,450  1,301,871
The protein
Catalyzed reaction/ biological activity
D-glucuronate --> D-fructuronate (according to UniProt)
aldehydo-D-galacturonate --> keto-D-tagaturonate (according to UniProt)
Protein family
Structure
3IAC (PDB) (from Salmonella typhimurium, 49% identity)
Expression and Regulation
Operons
Description
Regulation
induced by galacturonate (ExuR) PubMed
Regulatory mechanism
ExuR: repression, in the absence of inducer, in exuR regulon
CcpA: repression, PubMed PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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uxaCuxaA

2025-01-22 08:21:45

ghost

85

0325999ea185bfaaf2dea87e1701479c52256033

A15F6E93B04DC8C4B59B7976DAC34CE9AC0B8E51

Biological materials
Mutant
MGNA-A365 (yjmA::erm), available at the NBRP B. subtilis, Japan
BKE12300 (uxaC::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGTCCTCACCGTCTTTCA,  downstream forward: _UP4_TAACAAAGTGTCCGCTCAGT
BKK12300 (uxaC::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATGTCCTCACCGTCTTTCA,  downstream forward: _UP4_TAACAAAGTGTCCGCTCAGT
References
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5A0C29C7E218701727523885D01A48D02266B421

Page visits: 3359

Time of last update: 2025-01-30 16:34:50

Author of last update: Melvin.boenninger