yhcZ

yhcZ
168

two-component response regulator

Locus
BSU_09330
Molecular weight
23.88 kDa
Isoelectric point
5.9
Protein length
214 aaSequenceBlast
Gene length
645 bpSequenceBlast
Function
unknown
Product
two-component response regulator
Essential
no
Synonyms
yhcZ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2197 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,009,804 → 1,010,448
The protein
Domains
Response regulatory domain (aa 2-118) (according to UniProt)
HTH luxR-type domain (aa 142-207) (according to UniProt)
Structure
5HEV (PDB) (LiaR from Enterococcus faecium, 44% identity) PubMed
O07528 (AlphaFold)
Modification
phosphorylated on a Asp residue by YhcY
Paralogous protein(s)
YdfI, YxjL, LnrK, LiaR
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
yhcY-yhcZ-yhdA
Description
PubMed
Regulatory mechanism
LiaR: activation, PubMed, in liaR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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yhcY→yhdA

2025-04-02 10:01:23

ghost

85

8cc56cf62393d735d27584617b4d54806f9369b1

5E51555D7512C898216E1762D43B864CFD152408

Biological materials
Mutant
MGNA-A730 (yhcZ::erm), available at the NBRP B. subtilis, Japan
BKE09330 (ΔyhcZ::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TTTCATACCGCCCCTCCTTT,  downstream forward: _UP4_AAATGAACATGTTAGTCATA
BKK09330 (ΔyhcZ::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TTTCATACCGCCCCTCCTTT,  downstream forward: _UP4_AAATGAACATGTTAGTCATA
References
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Page visits: 4097

Time of last update: 2025-04-12 15:34:09

Author of last update: Melvin.boenninger