yhcN

yhcN
168

spore lipoprotein, required for spore germination and heat resistance

Locus
BSU_09150
Molecular weight
20.84 kDa
Isoelectric point
5.36
Protein length
189 aaSequenceBlast
Gene length
570 bpSequenceBlast
Function
efficient spore germination
Product
unknown
Essential
no
Synonyms
yhcN
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5912 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
989,022 → 989,591
Phenotypes of a mutant
reduced rate of spore germination in L-alanine PubMed
defective in GerA-mediated germination triggered by addition of L-valine PubMed
The protein
Domains
aa 1 - 24: lipobox (signal peptide and Cys for lipid binding) PubMed
aa 78 - 189: ring-building motif (RBM) domain PubMed
Structure
7PEG (PDB) PubMed
P54598 (AlphaFold)
Localization
forespore inner membrane (according to UniProt)
membrane around foreshores from 3 hrs after onset of Sporulation PubMed
Expression and Regulation
Operons
Genes
yhcN
Description
PubMed
Regulation
expressed during sporulation (SigF, SigG) PubMed
Sigma factors
SigF: sigma factor, PubMed, in sigF regulon
SigG: sigma factor, PubMed, in sigG regulon
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yhcN

2025-04-11 08:15:07

ghost

94

eeaf7b2f24faa27194d86cb6ab4eb3ad9017de72

7E238CB10A81EC0BA05C2738003784BB2046A60F

Additional information
the mRNA belongs to the 46 most abundant mRNA species in dormant spores PubMed
Biological materials
Mutant
MGNA-A671 (yhcN::erm), available at the NBRP B. subtilis, Japan
1A924 ( yhcN::erm), PubMed, available at BGSC
BKE09150 (ΔyhcN::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGAATTCCTCCTTTAT,  downstream forward: _UP4_TAAATGAAAGAAGCCGCACA
BKK09150 (ΔyhcN::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTGAATTCCTCCTTTAT,  downstream forward: _UP4_TAAATGAAAGAAGCCGCACA
References
Reviews
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Original Publications
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BA0E4135244D214B435836F07F608818A31B7E52

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Time of last update: 2025-04-12 16:12:06

Author of last update: Jstuelk