lplB

lplB
168

putative ABC transporter (permease)

Locus
BSU_07110
Molecular weight
36.42 kDa
Isoelectric point
9.31
Protein length
318 aaSequenceBlast
Gene length
957 bpSequenceBlast
Function
unknown
Product
unknown
Essential
no
Synonyms
lplB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4209 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
781,092  782,048
The protein
Protein family
Binding-protein-dependent transport system permease family (according to UniProt)
MalFG subfamily (according to UniProt)
Domains
ABC transmembrane type-1 domain (aa 90-305) (according to UniProt)
Structure
4TQU (PDB) (from Sphingomonas sp., 40% identity) PubMed
P39128 (AlphaFold)
Paralogous protein(s)
YteP
Localization
cell membrane PubMed
Biological materials
Mutant
BKE07110 (lplB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATCTGTTCTCCTTTCGT,  downstream forward: _UP4_GGATTGTTTTAGAGGAGGGA
BKK07110 (lplB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATCTGTTCTCCTTTCGT,  downstream forward: _UP4_GGATTGTTTTAGAGGAGGGA
References
Mahendran A, Orlando BJGenome wide structural prediction of ABC transporter systems in Bacillus subtilis.Frontiers in microbiology. 2024; 15:1469915. PMID: 39397791
O'Reilly FJ, Graziadei A, Forbrig C, Bremenkamp R, Charles K, Lenz S, Elfmann C, Fischer L, Stülke J, Rappsilber JProtein complexes in cells by AI-assisted structural proteomics.Molecular systems biology. 2023 Feb 23; :e11544. PMID: 36815589
Maruyama Y, Itoh T, Kaneko A, Nishitani Y, Mikami B, Hashimoto W, Murata K Structure of a Bacterial ABC Transporter Involved in the Import of an Acidic Polysaccharide Alginate. Structure (London, England : 1993). 2015 Sep 01; 23(9):1643-54. doi:10.1016/j.str.2015.06.021. pii:S0969-2126(15)00274-9. PMID:26235029
Quentin Y, Fichant G, Denizot F Inventory, assembly and analysis of Bacillus subtilis ABC transport systems. Journal of molecular biology. 1999 Apr 02; 287(3):467-84. . PMID:10092453

AA19541BCCAE08B48BD23F4E8337EBA220E5C4EF

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Time of last update: 2025-04-04 09:20:39

Author of last update: Jstuelk