rsbS

rsbS
168

part of the stressosome, control of SigB activity

Locus
BSU_04680
Molecular weight
13.17 kDa
Isoelectric point
4.14
Protein length
121 aaSequenceBlast
Gene length
366 bpSequenceBlast
Function
control of SigB activity
Product
scaffold protein of the stressosome, anti-RsbT
Essential
no
Synonyms
rsbS, ycxS
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1366 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
520,237  520,602
The protein
Domains
STAS domain (aa 4-115) (according to UniProt)
Structure
3VY9 (PDB) (complete stressosome)
6JHK (PDB)
P42410 (AlphaFold)
Modification
phosphorylation on Ser-59 by RsbT PubMed, dephosphorylation by RsbX PubMed
Expression and Regulation
Operons
Genes
rsbR-rsbS-rsbT-rsbU-rsbV-rsbW-sigB-rsbX
Description
PubMed
Regulation
''rsbV:'' induced by stress (SigB) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigB: sigma factor, PubMed, in sigB regulon
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rsbR→rsbX

2025-04-04 06:45:52

ghost

228

5f220975cc2493224a8aa0770ee2187c815a2127

3EFC8DC1AC54632D4F2AC30497749AB5CCA3A39F

Biological materials
Mutant
BKE04680 (rsbS::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CGGGATTTTCGGATGTCTCA,  downstream forward: _UP4_AAGCGGGAATTGGGGGAATA
BKK04680 (rsbS::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CGGGATTTTCGGATGTCTCA,  downstream forward: _UP4_AAGCGGGAATTGGGGGAATA
Labs working on this gene/protein
Bill Haldenwang, San Antonio, USA
Chet Price, Davis, USA homepage
References
Reviews
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Original Publications
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841CE7FCA4E84445830CA18F9856F6F30014E3BB

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Time of last update: 2025-04-06 15:35:13

Author of last update: Jstuelk