acpS

acpS
168

acyl-carrier protein synthase, 4-phosphopantetheine transferase

Locus
BSU_04620
Molecular weight
13.58 kDa
Isoelectric point
9.91
Protein length
121 aaSequenceBlast
Gene length
366 bpSequenceBlast
Function
fatty acid biosynthesis
Product
acyl-carrier protein synthase
Essential
yes
E.C.
2.7.8.7
Synonyms
acpS, ydcB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0736 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
515,710  516,075
Phenotypes of a mutant
essential PubMed
The protein
Catalyzed reaction/ biological activity
CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] --> adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein] (according to UniProt)
Protein family
P-Pant transferase superfamily (with Sfp/2, according to UniProt)
Cofactors
magnesium PubMed
Structure
1F7T (PDB) PubMed, 1F80 (PDB) (complex with AcpA) PubMed
P96618 (AlphaFold)
Localization
cytoplasm (according to Swiss-Prot)
Biological materials
Mutant
MGNA-C103 (ydcB::erm), available at the NBRP B. subtilis, Japan
BKE04620 (acpS::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTATGATAACCTCCTTT,  downstream forward: _UP4_TAGTCTGCATATTAGGGAAA
References
Reviews
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Original Publications
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Time of last update: 2025-04-16 17:54:52

Author of last update: Melvin.boenninger