hxlR

hxlR
168

MarR/DUF24 family transcription activator of the hxlA-hxlB operon

Locus
BSU_03470
Molecular weight
14.01 kDa
Isoelectric point
6.36
Protein length
120 aaSequenceBlast
Gene length
363 bpSequenceBlast
Function
regulation of the ribulose monophosphate pathway
Product
MarR/DUF24 family transcription activator
Essential
no
Synonyms
hxlR, yckH
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1733 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
376,032 → 376,394
The protein
Catalyzed reaction/ biological activity
transcription activation of the ribulose monophosphate pathway for formaldehyde fixation and detoxification
Protein family
MarR/DUF24 family
Domains
HTH hxlR-type domain (aa 11-110) (according to UniProt)
Structure
7BZD (PDB) PubMed
P42406 (AlphaFold)
Effectors of protein activity
formaldehyde stimulates transcription activation by HxlR PubMed
Paralogous protein(s)
YdzF, HypR, YdeP, YtcD, YkvN, YodB
Expression and Regulation
Operons
Genes
hxlR
Description
PubMed
Additional information
A ncRNA is predicted between hxlR and srfAA PubMed
Open in new tab

hxlR

2025-04-04 10:39:47

Jstuelk

80

759626dda146eb8c61f729d9b95940275d51fc22

348EDDD2846B2315164A6B62ED1E91A6CAE629AA

Biological materials
Mutant
BKE03470 (ΔhxlR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATAGAATCCCCCCCCTTA,  downstream forward: _UP4_TAAGACGCTCTTCGCAAGGG
BKK03470 (ΔhxlR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATAGAATCCCCCCCCTTA,  downstream forward: _UP4_TAAGACGCTCTTCGCAAGGG
References
Loading

D9A187961CFB9496A6712E9E48AAD384357A3E1C

Page visits: 6413

Time of last update: 2025-04-07 10:34:53

Author of last update: Jstuelk