skfH

skfH
168

unknown

Locus
BSU_01980
Molecular weight
16.08 kDa
Isoelectric point
4.82
Protein length
141 aaSequenceBlast
Gene length
426 bpSequenceBlast
Function
unknown
Product
unknown
Essential
no
Synonyms
skfH, ybdE
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
219,607 → 220,032
The protein
Domains
Thioredoxin domain (aa 2-141) (according to UniProt)
Structure
2HYX (PDB) (from Mycobacterium tuberculosis, 33% identity)
O31430 (AlphaFold)
Expression and Regulation
Operons
Genes
skfA-skfB-skfC-skfE-skfF-skfG-skfH
Description
PubMed
Regulation
expressed under conditions that trigger sporulation (Spo0A) PubMed
Regulatory mechanism
Spo0A: activation, PubMed, in spo0A regulon
AbrB: repression, PubMed, in abrB regulon
PhoP: activation, PubMed, in phoP regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
Northern blotting during during phosphate limitation showed an intense 0.25 kb 'skfA'-specific transcript, and a weaker 6.5 kb 'skfA-skfB-skfC-skfE-skfF-skfG-skfH' transcript.
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skfA→skfH

2025-03-31 01:14:49

ghost

166

f96cb932f6aa46632dc613334e3526e3904b2534

E1A5B1DE7F5A4653FA0FC2E7FE7AAD3454DBFF28

Biological materials
Mutant
MGNA-B954 (ybdE::erm), available at the NBRP B. subtilis, Japan
BKE01980 (ΔskfH::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCTTTCAGTCCTCCTTA,  downstream forward: _UP4_TGAAATTTTCCGTCTTGTAT
BKK01980 (ΔskfH::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCTTTCAGTCCTCCTTA,  downstream forward: _UP4_TGAAATTTTCCGTCTTGTAT
References
Reviews
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Original Publications
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F31B12F80AFC3580FD33811A1C22E74F75DC1A85

Page visits: 3714

Time of last update: 2025-04-13 20:07:01

Author of last update: Melvin.boenninger