rplGB

rplGB
168

highly expressed protein, similar to ribosomal protein L7AE family, associated with the ribosome during exponential growth, binds K-turns in RNA switches

Locus
BSU_01090
Molecular weight
8.33 kDa
Isoelectric point
9.51
Protein length
82 aaSequenceBlast
Gene length
249 bpSequenceBlast
Function
unknown
Product
unknown
Essential
no
Synonyms
ybxF, ybaB, rpmXB, ktuS
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1358 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
129,340  129,588
The protein
Catalyzed reaction/ biological activity
binds K-turns in RNA switches as they occur in the L-box, the S-box and the T-box PubMed
Protein family
Eukaryotic ribosomal protein eL8 family (with RplGA, according to UniProt)
Structure
3V7E (PDB) (RplGB bound to the [[S-box|SAM-I riboswitch]] aptamer) PubMed
P46350 (AlphaFold)
Localization
cytoplasm (according to UniProt)
Expression and Regulation
Operons
Genes
rplGB-rpsL-rpsG-fusA-tufA
Description
PubMed
Regulation
Rel dependent downregulation (Class I) during stringent response PubMed
the mRNA is processed between rplGB and rpsL by RNase Y, this requires the RicA-RicF-RicT complex PubMed
Regulatory mechanism
stringent response: negative regulation, PubMed, in stringent response
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rplGB->tufA

2025-04-07 00:23:29

Jstuelk

121

d846304cc2bd15e30cde627ac53b7d142c24fbb5

614BD7852C60161107389373FB106F44BAE4C835

Biological materials
Mutant
BKE01090 (rplGB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAAACATATCCTCCAAAG,  downstream forward: _UP4_TAACGTACTTTTGTTTTTGC
BKK01090 (rplGB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAAACATATCCTCCAAAG,  downstream forward: _UP4_TAACGTACTTTTGTTTTTGC
References
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11D7ABA61FC4069B48614875AF2C6C694291B545

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Time of last update: 2025-04-07 03:24:44

Author of last update: Jstuelk