cysE

cysE
168

serine O-acetyltransferase

Locus
BSU_00930
Molecular weight
24.00 kDa
Isoelectric point
9.49
Protein length
217 aaSequenceBlast
Gene length
654 bpSequenceBlast
Function
biosynthesis of cysteine
Product
serine O-acetyltransferase
Essential
no
E.C.
2.3.1.30
Synonyms
cysE, cysA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1045 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
112,800  113,453
Phenotypes of a mutant
poor growth PubMed
non-transformable PubMed
The protein
Catalyzed reaction/ biological activity
acetyl-CoA + L-serine --> CoA + O-acetyl-L-serine (according to UniProt)
Protein family
Transferase hexapeptide repeat family (according to UniProt)
Structure
1T3D (PDB) (from Escherichia coli, 48% identity, 64% similarity) PubMed
Q06750 (AlphaFold)
Localization
cytoplasm (according to UniProt)
Expression and Regulation
Operons
Genes
gltX-cysE-cysS-mrnC-yacO-rae1
Description
PubMed
Regulation
expression transiently increases in the forespore PubMed
the T-box RNA is degraded by RNase Y PubMed
Regulatory mechanism
T-box: RNA switch, overlaps a transcription terminator upstream of cysE, in T-box
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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gltX→rae1

2025-04-04 01:30:11

Jstuelk

96

9ab774439b3983729fe5811aeaf44f4bc16c609f

BCC6FA512C81F405B92E34AE44A52F949D245F3D

Biological materials
Mutant
BKE00930 (cysE::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACATGCTTCCCCCCGTTTC,  downstream forward: _UP4_AGAAAAGAAAGGATCAATCA
BKK00930 (cysE::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACATGCTTCCCCCCGTTTC,  downstream forward: _UP4_AGAAAAGAAAGGATCAATCA
References
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Page visits: 4676

Time of last update: 2025-04-05 05:17:29

Author of last update: Melvin.boenninger