Difference between revisions of "Fin"

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|style="background:#ABCDEF;" align="center"|'''Function''' || homologous recombination
 
|style="background:#ABCDEF;" align="center"|'''Function''' || homologous recombination
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00540 fin]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 8 kDa, 5.192   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 8 kDa, 5.192   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoVC]]'', ''[[mfd]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoVC]]'', ''[[mfd]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11830&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00540 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00540 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00540 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yabK_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yabK_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yabK_60130_60360_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:fin_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00540]]
 
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__TOC__
 
__TOC__
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* '''Locus tag:''' BSU00540
 
* '''Locus tag:''' BSU00540
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[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yabK_60130_60360_1 Expression]
 
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 
sporulation defect (50-fold reduction of viable spore count) and arrest after engulfment {{PubMed|21037003}}
 
sporulation defect (50-fold reduction of viable spore count) and arrest after engulfment {{PubMed|21037003}}
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00540&redirect=T BSU00540]
  
 
* '''DBTBS entry:''' no entry
 
* '''DBTBS entry:''' no entry
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=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00540&redirect=T BSU00540]
  
 
* '''Structure:'''
 
* '''Structure:'''
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* '''Operon:'''  
 
* '''Operon:'''  
  
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* '''[[Sigma factor]]:''' [[SigF]] {{PubMed|21037003}}, [[SigG]] {{PubMed|21037003}}
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yabK_60130_60360_1 fin] {{PubMed|22383849}}
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* '''Sigma factor:''' [[SigF]] {{PubMed|21037003}}, [[SigG]] {{PubMed|21037003}}
  
 
* '''Regulation:''' expressed in two waves in the forespore (after two hours ([[SigF]]) and three hours ([[SigG]]) after the onset of sporulation) {{PubMed|21037003}}
 
* '''Regulation:''' expressed in two waves in the forespore (after two hours ([[SigF]]) and three hours ([[SigG]]) after the onset of sporulation) {{PubMed|21037003}}
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
  
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* '''Additional information:'''  
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* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =

Latest revision as of 12:46, 2 April 2014

  • Description:
    • suppressor of recU mutations, participates in the stabilization and or processing of holliday junction intermediates PubMed
    • alternative description: antagonist to SigF, required for the switch from SigF- to SigG-dependent gene expression in the forespore PubMed

Gene name subA
Synonyms yabK
Essential no
Product unknown
Function homologous recombination
Gene expression levels in SubtiExpress: fin
MW, pI 8 kDa, 5.192
Gene length, protein length 228 bp, 76 aa
Immediate neighbours spoVC, mfd
Sequences Protein DNA DNA_with_flanks
Genetic context
YabK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Fin expression.png
























Categories containing this gene/protein

DNA repair/ recombination, sigma factors and their control, sporulation proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU00540

Phenotypes of a mutant

sporulation defect (50-fold reduction of viable spore count) and arrest after engulfment PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: localizes diffusely within the forespore compartment of sporangia at both early and late stages of sporulation, cytosolic protein PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: expressed in two waves in the forespore (after two hours (SigF) and three hours (SigG) after the onset of sporulation) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Begoña Carrasco, M Castillo Cozar, Rudi Lurz, Juan C Alonso, Silvia Ayora
Genetic recombination in Bacillus subtilis 168: contribution of Holliday junction processing functions in chromosome segregation.
J Bacteriol: 2004, 186(17);5557-66
[PubMed:15317759] [WorldCat.org] [DOI] (P p)

B Carrasco, S Fernández, K Asai, N Ogasawara, J C Alonso
Effect of the recU suppressors sms and subA on DNA repair and homologous recombination in Bacillus subtilis.
Mol Genet Genomics: 2002, 266(5);899-906
[PubMed:11810266] [WorldCat.org] [DOI] (P p)

Additional publications: PubMed

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