dgk

dgk
168

deoxyguanosine kinase

Locus
BSU_00150
Molecular weight
24.00 kDa
Isoelectric point
5.78
Protein length
207 aaSequenceBlast
Gene length
624 bpSequenceBlast
Function
purine salvage and interconversion
Product
deoxyguanosine kinase
Essential
no
E.C.
2.7.1.113
Synonyms
dgk, yaaG
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

List of homologs in different organisms, belongs to COG1428 (Galperin et al., 2021)

Gene
Coordinates
23,146  23,769
The protein
Catalyzed reaction/ biological activity
ATP + deoxyguanosine = ADP + dGMP (according to UniProt)
Protein family
DCK/DGK family (together woth Dck) (accoding to UniProt)
Structure
8PUU (PDB) (from Giardia intestinalis , 33% identity)
P37530 (AlphaFold)
Paralogous protein(s)
Dck
Localization
cytoplasm (accoding to UniProt)
Expression and Regulation
Operons
Genes
dgk-dck
Description
PubMed
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dgk→dck

2025-04-06 18:17:24

Jstuelk

103

a79e3573c7ef40ce7edc240f2c862e5e075bc687

5B80CB1DA13607F688D45E84AA89AAB4A93774D1

Biological materials
Mutant
MGNA-B888 (yaaG::erm), available at the NBRP B. subtilis, Japan
BKE00150 (dgk::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCGGAATCCTCCTTATAT,  downstream forward: _UP4_GCCCATGTAAAGGAGCTTAT
BKK00150 (dgk::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCGGAATCCTCCTTATAT,  downstream forward: _UP4_GCCCATGTAAAGGAGCTTAT
References
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Time of last update: 2025-04-06 11:21:43

Author of last update: Jstuelk