Difference between revisions of "YidC2"

From SubtiWiki
Jump to: navigation, search
(→‎References)
Line 4: Line 4:
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
−
|''yqjG''
+
|''yidC2''
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''oxaAB ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yqjG, oxaAB ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' ||  no
 
|style="background:#ABCDEF;" align="center"| '''Essential''' ||  no
Line 33: Line 33:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
−
 
 
<br/><br/>
 
<br/><br/>
  
Line 58: Line 57:
  
 
=== Additional information===
 
=== Additional information===
−
 
  
 
=The protein=
 
=The protein=
Line 66: Line 64:
 
* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
  
−
* '''Protein family:''' Type 2 subfamily (according to Swiss-Prot)
+
* '''Protein family:'''
  
 
* '''Paralogous protein(s):''' [[SpoIIIJ]], one of the two proteins has to be present for viability [http://www.ncbi.nlm.nih.gov/sites/entrez/17114254 PubMed]
 
* '''Paralogous protein(s):''' [[SpoIIIJ]], one of the two proteins has to be present for viability [http://www.ncbi.nlm.nih.gov/sites/entrez/17114254 PubMed]
Line 74: Line 72:
 
* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
−
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
−
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
Line 105: Line 103:
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=oxaAB_2483904_2484731_1 yidC2] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=oxaAB_2483904_2484731_1 yidC2] {{PubMed|22383849}}
  
−
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
Line 137: Line 135:
 
<pubmed>22688815 </pubmed>
 
<pubmed>22688815 </pubmed>
 
== Original publications ==
 
== Original publications ==
−
<pubmed>17114254, 15995216, 11889108, 12586834 19717609 19779460 21204254 22383849 22864117 </pubmed>
+
<pubmed>17114254, 15995216, 11889108, 12586834 19717609 19779460 21204254 22383849 22864117 24442413 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:12, 21 January 2014

  • Description: Sec-independent membrane protein translocase

Gene name yidC2
Synonyms yqjG, oxaAB
Essential no
Product Sec-independent membrane protein translocase
Function membrane insertion of proteins and protein secretion
MW, pI 30 kDa, 9.903
Gene length, protein length 825 bp, 275 aa
Immediate neighbours mifM, yqjF
Sequences Protein DNA DNA_with_flanks
Genetic context
YqjG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqjG expression.png















Categories containing this gene/protein

protein secretion, membrane proteins

This gene is a member of the following regulons

MifM regulon

The gene

Basic information

  • Locus tag: BSU23890

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): SpoIIIJ, one of the two proteins has to be present for viability PubMed

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
    • MifM: "attenuation mechanism", an mRNA hairpin of the yqjG transcript unfold upon translation arrest of MifM at decreased SpoIIIJ levels PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications

Markus Birkenmeier, Susanne Neumann, Thorsten Röder
Kinetic modeling of riboflavin biosynthesis in Bacillus subtilis under production conditions.
Biotechnol Lett: 2014, 36(5);919-28
[PubMed:24442413] [WorldCat.org] [DOI] (I p)

Shinobu Chiba, Koreaki Ito
Multisite ribosomal stalling: a unique mode of regulatory nascent chain action revealed for MifM.
Mol Cell: 2012, 47(6);863-72
[PubMed:22864117] [WorldCat.org] [DOI] (I p)

Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849] [WorldCat.org] [DOI] (I p)

Manfred J Saller, Andreas Otto, Greetje A Berrelkamp-Lahpor, Dörte Becher, Michael Hecker, Arnold J M Driessen
Bacillus subtilis YqjG is required for genetic competence development.
Proteomics: 2011, 11(2);270-82
[PubMed:21204254] [WorldCat.org] [DOI] (I p)

Shinobu Chiba, Anne Lamsa, Kit Pogliano
A ribosome-nascent chain sensor of membrane protein biogenesis in Bacillus subtilis.
EMBO J: 2009, 28(22);3461-75
[PubMed:19779460] [WorldCat.org] [DOI] (I p)

Manfred J Saller, Fabrizia Fusetti, Arnold J M Driessen
Bacillus subtilis SpoIIIJ and YqjG function in membrane protein biogenesis.
J Bacteriol: 2009, 191(21);6749-57
[PubMed:19717609] [WorldCat.org] [DOI] (I p)

Helena B Thomaides, Ella J Davison, Lisa Burston, Hazel Johnson, David R Brown, Alison C Hunt, Jeffery Errington, Lloyd Czaplewski
Essential bacterial functions encoded by gene pairs.
J Bacteriol: 2007, 189(2);591-602
[PubMed:17114254] [WorldCat.org] [DOI] (P p)

Aileen Rubio, Xin Jiang, Kit Pogliano
Localization of translocation complex components in Bacillus subtilis: enrichment of the signal recognition particle receptor at early sporulation septa.
J Bacteriol: 2005, 187(14);5000-2
[PubMed:15995216] [WorldCat.org] [DOI] (P p)

Harold Tjalsma, Sierd Bron, Jan Maarten van Dijl
Complementary impact of paralogous Oxa1-like proteins of Bacillus subtilis on post-translocational stages in protein secretion.
J Biol Chem: 2003, 278(18);15622-32
[PubMed:12586834] [WorldCat.org] [DOI] (P p)

Takako Murakami, Koki Haga, Michio Takeuchi, Tsutomu Sato
Analysis of the Bacillus subtilis spoIIIJ gene and its Paralogue gene, yqjG.
J Bacteriol: 2002, 184(7);1998-2004
[PubMed:11889108] [WorldCat.org] [DOI] (P p)

Retrieved from "http://subtiwiki.uni-goettingen.de/wiki//index.php?title=YidC2&oldid=197438"