MntC

• Description: manganese ABC transporter (membrane protein)
  
  

Gene name	mntC
Synonyms	ytgC
Essential	no
Product	manganese ABC transporter (membrane protein)
Function	manganese uptake
Gene expression levels in SubtiExpress: mntC
Interactions involving this protein in SubtInteract: MntC
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	47 kDa, 9.354
Gene length, protein length	1305 bp, 435 aa
Immediate neighbours	mntD, mntB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins

This gene is a member of the following regulons

MntR regulon

The gene

Basic information

• Locus tag: BSU30750

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC-3 integral membrane protein family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: MntB-(MntC-MntD)-MntA PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O35024

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: mntA-mntB-mntC-mntD PubMed

• Expression browser: mntC PubMed

• Sigma factor:

• Regulation:
  • repressed at high Mn(II) concentrations (MntR) PubMed

• Regulatory mechanism:
  • MntR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage