Difference between revisions of "NdoAI"
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| − | + | * '''Description:''' antitoxin, antagonist for [[NdoA|EndoA]] <br/><br/> | |
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| − | ** [[NdoAI]]-[[NdoA | + | ** [[NdoA]](2)-[[NdoAI]](2)-[[NdoA]](2) {{PubMed|24120662,17416361}} |
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
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* '''Structure:''' | * '''Structure:''' | ||
| + | ** [http://www.rcsb.org/pdb/explore.do?structureId=4ME7 4ME7] ([[NdoA]]-[[NdoAI]] complex) {{PubMed|24120662}} | ||
* '''UniProt:''' [http://www.uniprot.org/uniprot/P96621 P96621] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P96621 P96621] | ||
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=References= | =References= | ||
| − | <pubmed>17416361,15882409,, </pubmed> | + | <pubmed>17416361,15882409,24120662, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:23, 21 October 2013
- Description: antitoxin, antagonist for EndoA
| Gene name | ndoAI |
| Synonyms | ydcD |
| Essential | no |
| Product | antitoxin |
| Function | inhibition of NdoA |
| Gene expression levels in SubtiExpress: ndoAI | |
| Interactions involving this protein in SubtInteract: NdoAI | |
| MW, pI | 10 kDa, 6.138 |
| Gene length, protein length | 279 bp, 93 aa |
| Immediate neighbours | alr, ndoA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
toxins, antitoxins and immunity against toxins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04650
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: mazE/ndoAI family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P96621
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Dhirendra K Simanshu, Yoshihiro Yamaguchi, Jung-Ho Park, Masayori Inouye, Dinshaw J Patel
Structural basis of mRNA recognition and cleavage by toxin MazF and its regulation by antitoxin MazE in Bacillus subtilis.
Mol Cell: 2013, 52(3);447-58
[PubMed:24120662]
[WorldCat.org]
[DOI]
(I p)
Shivangi Agarwal, Shivani Agarwal, Rakesh Bhatnagar
Identification and characterization of a novel toxin-antitoxin module from Bacillus anthracis.
FEBS Lett: 2007, 581(9);1727-34
[PubMed:17416361]
[WorldCat.org]
[DOI]
(P p)
Olivier Pellegrini, Nathalie Mathy, Arhonda Gogos, Lawrence Shapiro, Ciarán Condon
The Bacillus subtilis ydcDE operon encodes an endoribonuclease of the MazF/PemK family and its inhibitor.
Mol Microbiol: 2005, 56(5);1139-48
[PubMed:15882409]
[WorldCat.org]
[DOI]
(P p)
