Difference between revisions of "NdoA"

From SubtiWiki
Jump to: navigation, search
(Database entries)
Line 84: Line 84:
  
 
* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
** [[NdoAI]]-[[NdoA]] {{PubMed|17416361}}
+
** [[NdoA]](2)-[[NdoAI]](2)-[[NdoA]](2) {{PubMed|24120662,17416361}}
 +
** the active protein forms dimers {{PubMed|24120662}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
Line 90: Line 91:
 
=== Database entries ===
 
=== Database entries ===
  
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1NE8 1NE8] {{PubMed|14517982}}
+
* '''Structure:'''  
 +
** [http://www.rcsb.org/pdb/explore.do?structureId=1NE8 1NE8] {{PubMed|14517982}}
 +
** [http://www.rcsb.org/pdb/explore.do?structureId=4MDX 4MDX] (NdoA-RNA) {{PubMed|24120662}}
 +
** [http://www.rcsb.org/pdb/explore.do?structureId=4ME7 4ME7] ([[NdoA]]-[[NdoAI]] complex) {{PubMed|24120662}}
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P96622 P96622]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P96622 P96622]
Line 135: Line 139:
 
=References=
 
=References=
  
<pubmed>15882409,17416361, 20525796 21763692 21897862 23378533 14517982 </pubmed>
+
<pubmed>15882409,17416361, 20525796 21763692 21897862 23378533 14517982 24120662</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 09:22, 21 October 2013

  • Description: RNase EndoA, MazF family toxin, UACAU-specific mRNA interferase

Gene name ndoA
Synonyms ydcE, mazF
Essential no
Product mRNA interferase
Function unknown
Gene expression levels in SubtiExpress: ndoA
Interactions involving this protein in SubtInteract: NdoA
MW, pI 12 kDa, 4.892
Gene length, protein length 348 bp, 116 aa
Immediate neighbours ndoAI, rsbR
Sequences Protein DNA DNA_with_flanks
Genetic context
YdcE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NdoA expression.png















Categories containing this gene/protein

Rnases, toxins, antitoxins and immunity against toxins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU04660

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: specifically cleaves a five-base sequence, UACAU PubMed
  • Protein family: pemK family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: the activity is inhibited by the interaction with NdoAI PubMed

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References