Difference between revisions of "NdoA"
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
− | ** [[NdoAI]]-[[NdoA]] {{PubMed|17416361}} | + | ** [[NdoA]](2)-[[NdoAI]](2)-[[NdoA]](2) {{PubMed|24120662,17416361}} |
+ | ** the active protein forms dimers {{PubMed|24120662}} | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
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=== Database entries === | === Database entries === | ||
− | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1NE8 1NE8] {{PubMed|14517982}} | + | * '''Structure:''' |
+ | ** [http://www.rcsb.org/pdb/explore.do?structureId=1NE8 1NE8] {{PubMed|14517982}} | ||
+ | ** [http://www.rcsb.org/pdb/explore.do?structureId=4MDX 4MDX] (NdoA-RNA) {{PubMed|24120662}} | ||
+ | ** [http://www.rcsb.org/pdb/explore.do?structureId=4ME7 4ME7] ([[NdoA]]-[[NdoAI]] complex) {{PubMed|24120662}} | ||
* '''UniProt:''' [http://www.uniprot.org/uniprot/P96622 P96622] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P96622 P96622] | ||
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=References= | =References= | ||
− | <pubmed>15882409,17416361, 20525796 21763692 21897862 23378533 14517982 </pubmed> | + | <pubmed>15882409,17416361, 20525796 21763692 21897862 23378533 14517982 24120662</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 09:22, 21 October 2013
- Description: RNase EndoA, MazF family toxin, UACAU-specific mRNA interferase
Gene name | ndoA |
Synonyms | ydcE, mazF |
Essential | no |
Product | mRNA interferase |
Function | unknown |
Gene expression levels in SubtiExpress: ndoA | |
Interactions involving this protein in SubtInteract: NdoA | |
MW, pI | 12 kDa, 4.892 |
Gene length, protein length | 348 bp, 116 aa |
Immediate neighbours | ndoAI, rsbR |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
Rnases, toxins, antitoxins and immunity against toxins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04660
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: specifically cleaves a five-base sequence, UACAU PubMed
- Protein family: pemK family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
Database entries
- UniProt: P96622
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
- An antisense RNA is predicted for ndoA PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References