Difference between revisions of "YwiE"
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| − | * '''Description:''' minor cardiolipin synthetase, general stress protein <br/><br/> | + | * '''Description:''' minor cardiolipin synthetase, general stress protein, required for protection against paraquat stress <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Product''' || minor cardiolipin synthetase | |style="background:#ABCDEF;" align="center"| '''Product''' || minor cardiolipin synthetase | ||
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || phospholipiid biosynthesis | + | |style="background:#ABCDEF;" align="center"|'''Function''' || phospholipiid biosynthesis, protection against paraquat stress |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU37240 ywiE] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU37240 ywiE] | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[biosynthesis of lipids]]}}, | {{SubtiWiki category|[[biosynthesis of lipids]]}}, | ||
{{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}}, | {{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}}, | ||
| + | {{SubtiWiki category|[[resistance against oxidative and electrophile stress]]}}, | ||
{{SubtiWiki category|[[membrane proteins]]}} | {{SubtiWiki category|[[membrane proteins]]}} | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| − | * '''Localization:''' cell membrane (according to Swiss-Prot) | + | * '''[[Localization]]:''' |
| + | ** cell membrane (according to Swiss-Prot) | ||
=== Database entries === | === Database entries === | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywiE_3821570_3823072_-1 ywiE] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywiE_3821570_3823072_-1 ywiE] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] | + | * '''[[Sigma factor]]:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] |
* '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] | * '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] | ||
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=References= | =References= | ||
| − | <pubmed>14973018 , 15805528, 16514141 </pubmed> | + | <pubmed>14973018 , 15805528,22582280 16514141 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:40, 15 September 2013
- Description: minor cardiolipin synthetase, general stress protein, required for protection against paraquat stress
| Gene name | ywiE |
| Synonyms | |
| Essential | no |
| Product | minor cardiolipin synthetase |
| Function | phospholipiid biosynthesis, protection against paraquat stress |
| Gene expression levels in SubtiExpress: ywiE | |
| Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis | |
| MW, pI | 58 kDa, 8.384 |
| Gene length, protein length | 1500 bp, 500 aa |
| Immediate neighbours | ywjA, narI |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of lipids, general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU37240
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2 Phosphatidylglycerol = diphosphatidylglycerol + glycerol (according to Swiss-Prot)
- Protein family: Cardiolipin synthase subfamily (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P45860
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Alexander Reder, Dirk Höper, Ulf Gerth, Michael Hecker
Contributions of individual σB-dependent general stress genes to oxidative stress resistance of Bacillus subtilis.
J Bacteriol: 2012, 194(14);3601-10
[PubMed:22582280]
[WorldCat.org]
[DOI]
(I p)
Claudia S López, Alejandro F Alice, Horacio Heras, Emilio A Rivas, Carmen Sánchez-Rivas
Role of anionic phospholipids in the adaptation of Bacillus subtilis to high salinity.
Microbiology (Reading): 2006, 152(Pt 3);605-616
[PubMed:16514141]
[WorldCat.org]
[DOI]
(P p)
Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528]
[WorldCat.org]
[DOI]
(P p)
Fumitaka Kawai, Momoko Shoda, Rie Harashima, Yoshito Sadaie, Hiroshi Hara, Kouji Matsumoto
Cardiolipin domains in Bacillus subtilis marburg membranes.
J Bacteriol: 2004, 186(5);1475-83
[PubMed:14973018]
[WorldCat.org]
[DOI]
(P p)
