snaB

snaB
168

S-(2-succino)cysteine N-acetyltransferase

Locus
BSU_39510
Molecular weight
18.88 kDa
Isoelectric point
9.12
Protein length
165 aaSequenceBlast
Gene length
498 bpSequenceBlast
Function
utilization and detoxification of S-(2-succino)cysteine
Product
S-(2-succino)cysteine N-acetyltransferase
Essential
no
Synonyms
snaB, yxeL
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0456 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,060,307 → 4,060,804
Phenotypes of a mutant
the ''snaA snaB'' double mutant does not grow with S-methyl cysteine PubMed
no growth with S-(2-succino)cysteine as the single source of sulfur PubMed
resistant to S-(2-succino)cysteine toxicity PubMed
RNA
Catalyzed reaction/ biological activity
acetylation of S-(2-succino)cysteine PubMed
The protein
Protein family
Acetyltransferase family (according to UniProt)
Domains
N-acetyltransferase domain (aa 3-162) (according to UniProt)
Structure
P54951 (AlphaFold)
Paralogous protein(s)
SnaA
Expression and Regulation
Operons
Genes
yxeK-snaB-yxeM-yxeN-yxeO-sndB-yxeQ
Description
PubMed
Regulation
repressed in the presence of cysteine (CymR) PubMed
Regulatory mechanism
CymR: repression, PubMed, in cymR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed
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yxeK→yxeQ

2025-03-31 02:55:29

Bzhu

101

26e7d8a77b7f64e210508bce49d61eed26cdd5aa

11F447FD5833B59A1639842D70685F9A6B369EAF

Biological materials
Mutant
MGNA-B781 (yxeL::erm), available at the NBRP B. subtilis, Japan
BKE39510 (ΔsnaB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TCGTGGCTTCATCTAGCGTT,  downstream forward: _UP4_TAAAAATAGAAAAGGCGGGA
BKK39510 (ΔsnaB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TCGTGGCTTCATCTAGCGTT,  downstream forward: _UP4_TAAAAATAGAAAAGGCGGGA
References
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EBC2B9107AD50DD8F8174FC0BE4AD90DEE6A7CCA

Page visits: 4661

Time of last update: 2025-04-13 10:39:15

Author of last update: Melvin.boenninger