Difference between revisions of "CotZ"

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(Extended information on the protein)
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
{{SubtiWiki regulon|[[GerE regulon]]}},
 
{{SubtiWiki regulon|[[GerE regulon]]}},
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{{SubtiWiki regulon|[[SigE regulon]]}},
 
{{SubtiWiki regulon|[[SigK regulon]]}}
 
{{SubtiWiki regulon|[[SigK regulon]]}}
  
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* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
** outermost layer of the spore coat (crust) {{PubMed|22171814}}
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** outermost layer of the spore coat (crust), localization depends on [[CotE]] {{PubMed|22171814}}
 
** more abundant at the mother cell-proximal pole of the forespore  {{PubMed|19933362,21665972}}
 
** more abundant at the mother cell-proximal pole of the forespore  {{PubMed|19933362,21665972}}
  
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotZ_1249442_1249888_-1 cotZ] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotZ_1249442_1249888_-1 cotZ] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigK]] {{PubMed|7519271,15699190}}
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* '''Sigma factor:''' [[SigK]] {{PubMed|7519271,15699190}}, [[SigE]] {{PubMed|15383836}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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=References=
 
=References=
  
<pubmed>19304857,7519271,15699190, 19933362 20451384 21665972 22171814</pubmed>
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<pubmed>19304857,7519271,15699190, 19933362 20451384 21665972 22171814 15383836 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 15:16, 13 August 2013

  • Description: spore crust protein (insoluble fraction), necessary for the assembly of the spore crust, the outermost layer of the spore coat

Gene name cotZ
Synonyms
Essential no
Product spore crust protein (insoluble fraction)
Function spore crust assembly
Gene expression levels in SubtiExpress: cotZ
Interactions involving this protein in SubtInteract: CotZ
MW, pI 16 kDa, 5.102
Gene length, protein length 444 bp, 148 aa
Immediate neighbours cotO, cotY
Sequences Protein DNA DNA_with_flanks
Genetic context
CotZ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CotZ expression.png















Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

GerE regulon, SigE regulon, SigK regulon

The gene

Basic information

  • Locus tag: BSU11740

Phenotypes of a mutant

  • mis-assembly of the spore crust PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • outermost layer of the spore coat (crust), localization depends on CotE PubMed
    • more abundant at the mother cell-proximal pole of the forespore PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References