CtaC

• Description: cytochrome-c oxidase (subunit II)
  
  

Gene name	ctaC
Synonyms
Essential	no
Product	cytochrome-c oxidase (subunit II)
Function	respiration
Gene expression levels in SubtiExpress: ctaC
Interactions involving this protein in SubtInteract: CtaC
MW, pI	39 kDa, 8.635
Gene length, protein length	1068 bp, 356 aa
Immediate neighbours	ctaB, ctaD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

respiration, membrane proteins

This gene is a member of the following regulons

Abh regulon, AbrB regulon, CcpA regulon, ResD regulon

The gene

Basic information

• Locus tag: BSU14890

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 4 ferrocytochrome c + O₂ + 4 H⁺ = 4 ferricytochrome c + 2 H₂O (according to Swiss-Prot)

• Protein family: cytochrome c oxidase subunit 2 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): 2 heme A molecules, Cu(A) PubMed

• Effectors of protein activity:

• Interactions:
  • Sco-CtaC PubMed
  • KinB-CtaC PubMed
  • part of a respiratory supercomplex PubMed
  • CtaC-CtaE PubMed

• Localization:
  • cell membrane PubMed

Database entries

• Structure:

• UniProt: P24011

• KEGG entry: [3]

• E.C. number: 1.9.3.1

Expression and regulation

• • Operon: ctaB-ctaC-ctaD-ctaE-ctaF-ctaG PubMed

• Expression browser: ctaC PubMed

• Sigma factor:

• Regulation:
  • expressed under anaerobic conditions (ResD) PubMed
  • repressed by glucose (11-fold) (CcpA) PubMed

• Regulatory mechanism:
  • ResD: transcription activation PubMed
  • CcpA: transcription repression
  • Abh and AbrB: synergistic transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: