Difference between revisions of "TrxB"
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=trxB_3573207_3574157_-1 trxB] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=trxB_3573207_3574157_-1 trxB] {{PubMed|22383849}} | ||
− | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
+ | == Reviews == | ||
+ | <pubmed> 23899494 </pubmed> | ||
+ | == Original publications == | ||
<pubmed> 20084284 12642660 20525796</pubmed> | <pubmed> 20084284 12642660 20525796</pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 11:28, 1 August 2013
- Description: thioredoxin reductase (NADPH)
Gene name | trxB |
Synonyms | yvcH |
Essential | yes PubMed |
Product | thioredoxin reductase (NADPH) |
Function | keeps thioredoxin in the reduced state |
Gene expression levels in SubtiExpress: trxB | |
MW, pI | 34 kDa, 4.99 |
Gene length, protein length | 948 bp, 316 aa |
Immediate neighbours | yvcI, cwlO |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
electron transport/ other, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU34790
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Thioredoxin + NADP+ = thioredoxin disulfide + NADPH (according to Swiss-Prot)
- Protein family: class-II pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P80880
- KEGG entry: [2]
- E.C. number: 1.8.1.9
Additional information
Expression and regulation
- Operon:
- Regulation:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Jun Lu, Arne Holmgren
The thioredoxin antioxidant system.
Free Radic Biol Med: 2014, 66;75-87
[PubMed:23899494]
[WorldCat.org]
[DOI]
(I p)
Original publications