Difference between revisions of "FtsX"
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| − | * '''Description:''' [[ABC transporter]] (membrane protein) ([[FtsE]]-[[FtsX]]), required for proper activation of [[Spo0A]] and initiation of sporulation <br/><br/> | + | * '''Description:''' [[ABC transporter]] (membrane protein) ([[FtsE]]-[[FtsX]]), required for [[CwlO]] activity and for proper activation of [[Spo0A]] and initiation of [[sporulation]] <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] (membrane protein) | |style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] (membrane protein) | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[cell wall synthesis]] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35250 ftsX] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35250 ftsX] | ||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[ABC transporters]]}}, | {{SubtiWiki category|[[ABC transporters]]}}, | ||
| + | {{SubtiWiki category|[[cell wall synthesis]]}}, | ||
{{SubtiWiki category|[[phosphorelay]]}}, | {{SubtiWiki category|[[phosphorelay]]}}, | ||
{{SubtiWiki category|[[membrane proteins]]}} | {{SubtiWiki category|[[membrane proteins]]}} | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * a ''[[ftsX]]'' mutation is synthetically lethal with a ''[[lytE]]'' mutation (due to a lack of autolysin activity) {{PubMed|xxx}} | ||
| + | * shorter, fatter cells {{PubMed|xxx}} | ||
=== Database entries === | === Database entries === | ||
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=== Additional information=== | === Additional information=== | ||
| − | |||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** necessary for the autolysin activity of [[CwlO]] {{PubMed|xxx}} | ||
* '''Protein family:''' FtsX subfamily (according to Swiss-Prot) | * '''Protein family:''' FtsX subfamily (according to Swiss-Prot) | ||
Revision as of 12:02, 16 July 2013
- Description: ABC transporter (membrane protein) (FtsE-FtsX), required for CwlO activity and for proper activation of Spo0A and initiation of sporulation
| Gene name | ftsX |
| Synonyms | |
| Essential | no |
| Product | ABC transporter (membrane protein) |
| Function | control of cell wall synthesis |
| Gene expression levels in SubtiExpress: ftsX | |
| Interactions involving this protein in SubtInteract: FtsX | |
| MW, pI | 32 kDa, 10.016 |
| Gene length, protein length | 888 bp, 296 aa |
| Immediate neighbours | ctpB, ftsE |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
ABC transporters, cell wall synthesis, phosphorelay, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35250
Phenotypes of a mutant
- a ftsX mutation is synthetically lethal with a lytE mutation (due to a lack of autolysin activity) PubMed
- shorter, fatter cells PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: FtsX subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed
Database entries
- Structure:
- UniProt: O34876
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
