Difference between revisions of "MutM"
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Revision as of 14:15, 16 May 2013
- Description: formamidopyrimidine-DNA glycosidase
Gene name | mutM |
Synonyms | ytaE |
Essential | no |
Product | formamidopyrimidine-DNA glycosidase |
Function | DNA repair |
Gene expression levels in SubtiExpress: mutM | |
MW, pI | 31 kDa, 8.889 |
Gene length, protein length | 834 bp, 278 aa |
Immediate neighbours | ytaF, polA |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29080
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine (according to Swiss-Prot)
- Protein family: FPG family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 2F5S (complex with oxoG:C, Geobacillus stearothermophilus)
- UniProt: O34403
- KEGG entry: [2]
- E.C. number: 3.2.2.23
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References