Difference between revisions of "MutM"

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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mutM_2972329_2973159_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:mutM_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29080]]
 
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Revision as of 14:15, 16 May 2013

  • Description: formamidopyrimidine-DNA glycosidase

Gene name mutM
Synonyms ytaE
Essential no
Product formamidopyrimidine-DNA glycosidase
Function DNA repair
Gene expression levels in SubtiExpress: mutM
MW, pI 31 kDa, 8.889
Gene length, protein length 834 bp, 278 aa
Immediate neighbours ytaF, polA
Sequences Protein DNA DNA_with_flanks
Genetic context
MutM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MutM expression.png
























Categories containing this gene/protein

DNA repair/ recombination

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU29080

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine (according to Swiss-Prot)
  • Protein family: FPG family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2F5S (complex with oxoG:C, Geobacillus stearothermophilus)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References