Difference between revisions of "MurE"
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| − | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=murE_1586330_1587814_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:murE_expression.png|500px]] | + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=murE_1586330_1587814_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:murE_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15180]] |
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Revision as of 13:14, 16 May 2013
- Description: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase
| Gene name | murE |
| Synonyms | |
| Essential | yes PubMed |
| Product | UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl- meso-2,6-diaminopimelate synthetase |
| Function | peptidoglycan precursor biosynthesis |
| Gene expression levels in SubtiExpress: murE | |
| Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr, Cell wall | |
| MW, pI | 54 kDa, 5.558 |
| Gene length, protein length | 1482 bp, 494 aa |
| Immediate neighbours | spoVD, mraY |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15180
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diamino-heptanedioate (according to Swiss-Prot)
- Protein family: MurE subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: Q03523
- KEGG entry: [3]
- E.C. number: 6.3.2.13
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
