Difference between revisions of "SigI"
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Revision as of 13:06, 16 May 2013
- Description: RNA polymerase sigma factor SigI
| Gene name | sigI |
| Synonyms | ykoZ |
| Essential | no |
| Product | RNA polymerase sigma factor SigI |
| Function | control of a class of heat shock genes |
| Gene expression levels in SubtiExpress: sigI | |
| Interactions involving this protein in SubtInteract: SigI | |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 29 kDa, 8.306 |
| Gene length, protein length | 753 bp, 251 aa |
| Immediate neighbours | ykoY, rsgI |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription, sigma factors and their control, heat shock proteins
This gene is a member of the following regulons
The SigI regulon: bcrC, gsiB, lytE, mreBH, sigI-rsgI
The gene
Basic information
- Locus tag: BSU13450
Phenotypes of a mutant
- temperature-sensitive growth on agar plates PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31654
- KEGG entry: [3]
- E.C. number:
Additional information
overexpression of SigI suppresses mreB mreBH mbl mutants PubMed
Expression and regulation
- Regulation: induced by heat PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Chi-Ling Tseng, Jung-Tze Chen, Ju-Hui Lin, Wan-Zhen Huang, Gwo-Chyuan Shaw
Genetic evidence for involvement of the alternative sigma factor SigI in controlling expression of the cell wall hydrolase gene lytE and contribution of LytE to heat survival of Bacillus subtilis.
Arch Microbiol: 2011, 193(9);677-85
[PubMed:21541672]
[WorldCat.org]
[DOI]
(I p)
Kathrin Schirner, Jeff Errington
The cell wall regulator {sigma}I specifically suppresses the lethal phenotype of mbl mutants in Bacillus subtilis.
J Bacteriol: 2009, 191(5);1404-13
[PubMed:19114499]
[WorldCat.org]
[DOI]
(I p)
Chi-Ling Tseng, Gwo-Chyuan Shaw
Genetic evidence for the actin homolog gene mreBH and the bacitracin resistance gene bcrC as targets of the alternative sigma factor SigI of Bacillus subtilis.
J Bacteriol: 2008, 190(5);1561-7
[PubMed:18156261]
[WorldCat.org]
[DOI]
(I p)
Kei Asai, Takafumi Ootsuji, Kazue Obata, Takashi Matsumoto, Yasutaro Fujita, Yoshito Sadaie
Regulatory role of RsgI in sigI expression in Bacillus subtilis.
Microbiology (Reading): 2007, 153(Pt 1);92-101
[PubMed:17185538]
[WorldCat.org]
[DOI]
(P p)
U Zuber, K Drzewiecki, M Hecker
Putative sigma factor SigI (YkoZ) of Bacillus subtilis is induced by heat shock.
J Bacteriol: 2001, 183(4);1472-5
[PubMed:11157964]
[WorldCat.org]
[DOI]
(P p)
