Difference between revisions of "TilS"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yabT]]'', ''[[hprT]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yabT]]'', ''[[hprT]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00670 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00670 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00670 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00670 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00670 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00670 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yacA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yacA_context.gif]]

Revision as of 09:12, 14 May 2013

  • Description: tRNAIle-lysidine synthetase

Gene name tilS
Synonyms yacA
Essential yes PubMed
Product tRNAIle-lysidine synthetase
Function tRNA modification
Gene expression levels in SubtiExpress: tilS
Metabolic function and regulation of this protein in SubtiPathways:
Nucleotides (regulation)
MW, pI 53 kDa, 8.317
Gene length, protein length 1416 bp, 472 aa
Immediate neighbours yabT, hprT
Sequences Protein DNA DNA_with_flanks
Genetic context
YacA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TilS expression.png




























Categories containing this gene/protein

translation, cell envelope stress proteins (controlled by SigM, V, W, X, Y), essential genes

This gene is a member of the following regulons

SigM regulon

The gene

Basic information

  • Locus tag: BSU00670

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: tRNA(Ile)-lysidine synthase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3A2K (from Geobacillus kaustophilus, complex with tRNA) PubMed
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications