Difference between revisions of "PolY1"
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|style="background:#ABCDEF;" align="center"|'''Function''' || generation of mutations in stationary phase | |style="background:#ABCDEF;" align="center"|'''Function''' || generation of mutations in stationary phase | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23870 polY1] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gndA]]'', ''[[mifM]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gndA]]'', ''[[mifM]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU23870 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU23870 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU23870 Advanced_DNA] |
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Revision as of 13:14, 13 May 2013
- Description: translesion synthesis (TLS-) DNA polymerase Y1, important for stationary phase mutagenesis
| Gene name | polY1 |
| Synonyms | yqjH |
| Essential | no |
| Product | translesion synthesis (TLS-) DNA polymerase Y1 |
| Function | generation of mutations in stationary phase |
| Gene expression levels in SubtiExpress: polY1 | |
| Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
| MW, pI | 46 kDa, 9.953 |
| Gene length, protein length | 1242 bp, 414 aa |
| Immediate neighbours | gndA, mifM |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23870
Phenotypes of a mutant
reduced UV-induced mutagenesis PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1) (according to Swiss-Prot)
- Protein family: DNA polymerase type-Y family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (homogeneous)
Database entries
- Structure:
- UniProt: P54545
- KEGG entry: [3]
- E.C. number: 2.7.7.7
Additional information
Expression and regulation
- Sigma factor:
- Regulation: constitutively expressed PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: GP1111 (spc), available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
