Difference between revisions of "CpgA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || ribosome assembly, coordination of peptidoglycan deposition in the cell wall
 
|style="background:#ABCDEF;" align="center"|'''Function''' || ribosome assembly, coordination of peptidoglycan deposition in the cell wall
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU15780 cpgA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15780 cpgA]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[prkC]]'', ''[[rpe]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[prkC]]'', ''[[rpe]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13451&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15780 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15780 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15780 Advanced_DNA]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yloQ_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yloQ_context.gif]]

Revision as of 12:48, 13 May 2013

  • Description: GTPase, activity stimulated by ribosomes, may be involved in ribosome maturation

Gene name cpgA
Synonyms yloQ
Essential no
Product GTPase
Function ribosome assembly, coordination of peptidoglycan deposition in the cell wall
Gene expression levels in SubtiExpress: cpgA
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 33 kDa, 4.743
Gene length, protein length 894 bp, 298 aa
Immediate neighbours prkC, rpe
Sequences Protein DNA Advanced_DNA
Genetic context
YloQ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CpgA expression.png




























Categories containing this gene/protein

cell wall/ other, translation, GTP-binding proteins, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15780

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: engC GTPase domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • in vitro phosphorylated on Thr-166 by PrkC, dephosphorylated by PrpC PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Tony Wilkinson, York University, U.K. homepage

Your additional remarks

References

Reviews

Robert A Britton
Role of GTPases in bacterial ribosome assembly.
Annu Rev Microbiol: 2009, 63;155-76
[PubMed:19575570] [WorldCat.org] [DOI] (I p)

Original publications