NupG

• Description: purine nucleoside transporter
  
  

Gene name	nupG
Synonyms	yxjA
Essential	no
Product	purine nucleoside transporter
Function	purine uptake
Gene expression levels in SubtiExpress: nupG
MW, pI	43 kDa, 7.757
Gene length, protein length	1191 bp, 397 aa
Immediate neighbours	yxjB, yxiT/1
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, biosynthesis/ acquisition of nucleotides, membrane proteins

This gene is a member of the following regulons

G-box

The gene

Basic information

• Locus tag: BSU39020

Phenotypes of a mutant

• a nupN nupG double mutant is unable to utilize externally provided guanosine PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: SLC28A transporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane PubMed

Database entries

• Structure:

• UniProt: P42312

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: nupG

• Expression browser: nupG PubMed

• Sigma factor:

• Regulation:
  • expression activated by glucose (4.3 fold) PubMed
  • repressed by hypoxanthine and guanine, PurR-independent, G-boxPubMed

• Regulatory mechanism: G-box: transcriptional termination/ antitermination riboswitch PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: