Difference between revisions of "ThiL"

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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 975 bp, 325 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 975 bp, 325 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[trnE-Asp]]'', ''[[ydiB]]''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[trnE-Asp]]'', ''[[tsaE]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12409&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12409&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''

Revision as of 11:22, 18 October 2012

  • Description: thiamine-monophosphate kinase

Gene name thiL
Synonyms ydiA, ydxA
Essential no
Product thiamine-monophosphate kinase
Function biosynthesis of thiamine
Gene expression levels in SubtiExpress: thiL
Metabolic function and regulation of this protein in SubtiPathways:
Thiamin
MW, pI 35 kDa, 5.036
Gene length, protein length 975 bp, 325 aa
Immediate neighbours trnE-Asp, tsaE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ThiL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ThiL expression.png















Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU05900

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + thiamine phosphate = ADP + thiamine diphosphate (according to Swiss-Prot)
  • Protein family: thiamine-monophosphate kinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1VQV (from Aquifex aeolicus, 33% similarity, 51% identity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications