EbrA

• Description: multidrug efflux transporter
  
  

Gene name	ebrA
Synonyms
Essential	no
Product	multidrug efflux transporter
Function	multidrug resistance
Gene expression levels in SubtiExpress: ebrA
Interactions involving this protein in SubtInteract: EbrA
MW, pI	11 kDa, 9.373
Gene length, protein length	315 bp, 105 aa
Immediate neighbours	ebrB, ymaG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, resistance against toxins/ antibiotics, membrane proteins

The gene

Basic information

• Locus tag: BSU17300

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): EbrB

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: EbrA-EbrB PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: O31792

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ebrA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Zhongge Zhang, Che Ma, Owen Pornillos, Xia Xiu, Geoffrey Chang, Milton H Saier
Functional characterization of the heterooligomeric EbrAB multidrug efflux transporter of Bacillus subtilis.
Biochemistry: 2007, 46(17);5218-25
[PubMed:17417881] [WorldCat.org] [DOI] (P p)