Difference between revisions of "PgcA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || interconversion of glucose 6-phosphate and alpha-glucose 1-phosphate | |style="background:#ABCDEF;" align="center"|'''Function''' || interconversion of glucose 6-phosphate and alpha-glucose 1-phosphate | ||
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| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU09310 pgcA] | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_synthesis.html Lipid synthesis]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_synthesis.html Lipid synthesis]''' | ||
Revision as of 16:15, 6 August 2012
| Gene name | pgcA |
| Synonyms | yhxB, gtaC, gtaE |
| Essential | no |
| Product | alpha-phosphoglucomutase |
| Function | interconversion of glucose 6-phosphate and alpha-glucose 1-phosphate |
| Gene expression levels in SubtiExpress: pgcA | |
| Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis | |
| MW, pI | 62 kDa, 4.913 |
| Gene length, protein length | 1695 bp, 565 aa |
| Immediate neighbours | glpD, yhcY |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall synthesis, lipid metabolism/ other, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU09310
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate (according to Swiss-Prot)
- Protein family: phosphohexose mutase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P18159
- KEGG entry: [2]
- E.C. number: 5.4.2.2
Additional information
PgcA inhibits FtsZ ring assembly (indirect effect due to a defect in UDP-glucose synthesis)PubMed
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Massimiliano Marvasi, Pieter T Visscher, Lilliam Casillas Martinez
Exopolymeric substances (EPS) from Bacillus subtilis: polymers and genes encoding their synthesis.
FEMS Microbiol Lett: 2010, 313(1);1-9
[PubMed:20735481]
[WorldCat.org]
[DOI]
(I p)
Original publications
Additional publications: PubMed
