Difference between revisions of "YszB"

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Revision as of 10:06, 20 April 2012

  • Description: chorismate mutase

Gene name pheB
Synonyms
Essential no
Product chorismate mutase
Function biosynthesis of phenylalanine
Metabolic function and regulation of this protein in SubtiPathways:
Phe, Tyr, Trp
MW, pI 16 kDa, 6.36
Gene length, protein length 441 bp, 147 aa
Immediate neighbours pheA, obg
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PheB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PheB expression.png




























Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU27910

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: UPF0735 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Frederik Claeyssens, Kara E Ranaghan, Narin Lawan, Stephen J Macrae, Frederick R Manby, Jeremy N Harvey, Adrian J Mulholland
Analysis of chorismate mutase catalysis by QM/MM modelling of enzyme-catalysed and uncatalysed reactions.
Org Biomol Chem: 2011, 9(5);1578-90
[PubMed:21243152] [WorldCat.org] [DOI] (I p)

K Trach, J A Hoch
The Bacillus subtilis spo0B stage 0 sporulation operon encodes an essential GTP-binding protein.
J Bacteriol: 1989, 171(3);1362-71
[PubMed:2537815] [WorldCat.org] [DOI] (P p)