XylR

• Description: transcriptional repressor of the xylA-xylB and xynP-xynB operons
  
  

Gene name	xylR
Synonyms
Essential	no
Product	transcriptional repressor
Function	regulation of xylan and xylose utilization
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	38 kDa, 5.819
Gene length, protein length	1050 bp, 350 aa
Immediate neighbours	xynB, xylA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

The XylR regulon

• xylA-xylB, xynP-xynB

The gene

Basic information

• Locus tag: BSU17590

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transcription repression of the xylA-xylB and the xynP-xynB operons

• Protein family: ROK (nagC/xylR) family (according to Swiss-Prot)

• Paralogous protein(s): GlcK

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: inducer: xylose

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P94490

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: xylR (according to DBTBS)

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: GP270 (erm), GP1302 (aphA3), available in the Stülke lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Wolfgang Hillen, Erlangen University, Germany Homepage