SpoIIB

• Description: spatial and temporal regulation of the dissolution of septal peptidoglycan during engulfment
  
  

Gene name	spoIIB
Synonyms
Essential	no
Product	facilitator of septal dissolution
Function	spore morphogenesis
MW, pI	35 kDa, 4.797
Gene length, protein length	996 bp, 332 aa
Immediate neighbours	maf, comC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

sporulation/ other

The gene

Basic information

• Locus tag: BSU28060

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P37575

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: spoIIB PubMed

• Sigma factor:

• Regulation:
  • repressed by casamino acids PubMed
  • expression is reduced in a SigV mutant PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Arnaud Chastanet, Richard Losick
Engulfment during sporulation in Bacillus subtilis is governed by a multi-protein complex containing tandemly acting autolysins.
Mol Microbiol: 2007, 64(1);139-52
[PubMed:17376078] [WorldCat.org] [DOI] (P p)

Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147] [WorldCat.org] [DOI] (P p)

O Resnekov, A Driks, R Losick
Identification and characterization of sporulation gene spoVS from Bacillus subtilis.
J Bacteriol: 1995, 177(19);5628-35
[PubMed:7559352] [WorldCat.org] [DOI] (P p)

P S Margolis, A Driks, R Losick
Sporulation gene spoIIB from Bacillus subtilis.
J Bacteriol: 1993, 175(2);528-40
[PubMed:8419299] [WorldCat.org] [DOI] (P p)