BceS

• Description: two-component sensor kinase, regulation of bceA-bceB in response to bacitracin, plectasin, mersacidin and actagardine
  
  

Gene name	bceS
Synonyms	ytsB
Essential	no
Product	two-component sensor kinase (OmpR family)
Function	resistance against toxic peptides
MW, pI	38 kDa, 5.939
Gene length, protein length	1002 bp, 334 aa
Immediate neighbours	bceA, bceR
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

protein modification, transcription factors and their control, resistance against toxins/ antibiotics, membrane proteins, phosphoproteins

The gene

Basic information

• Locus tag: BSU30390

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of BceR

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain

• Modification: autophosphorylation on a His residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • BceS-BceR
  • BceB-BceS PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O35044

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: bceR-bceS PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed