Difference between revisions of "BrxA"
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| − | * '''Description:''' disulfide isomerase <br/><br/> | + | * '''Description:''' disulfide isomerase, putative bacilliredoxin <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || disulfide isomerase | + | |style="background:#ABCDEF;" align="center"| '''Product''' || disulfide isomerase, putative bacilliredoxin |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown | |style="background:#ABCDEF;" align="center"|'''Function''' || unknown | ||
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=== Additional information=== | === Additional information=== | ||
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| − | |||
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=The protein= | =The protein= | ||
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* '''Domains:''' contains an CxC redox motif [http://www.ncbi.nlm.nih.gov/pubmed/20308541] | * '''Domains:''' contains an CxC redox motif [http://www.ncbi.nlm.nih.gov/pubmed/20308541] | ||
| − | * '''Modification:''' | + | * '''Modification:''' |
| + | ** S-bacillithiolation upon hypochlorite stress on Cys-53 {{PubMed|21749987}} | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
* '''Localization:''' | * '''Localization:''' | ||
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=References= | =References= | ||
| − | <pubmed> 19653655 20308541</pubmed> | + | <pubmed> 19653655 20308541 21749987</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:27, 14 July 2011
- Description: disulfide isomerase, putative bacilliredoxin
| Gene name | yphP |
| Synonyms | |
| Essential | no |
| Product | disulfide isomerase, putative bacilliredoxin |
| Function | unknown |
| MW, pI | 15 kDa, 4.619 |
| Gene length, protein length | 432 bp, 144 aa |
| Immediate neighbours | ypiP, ilvD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
poorly characterized/ putative enzymes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU21860
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: scpA family (according to Swiss-Prot)
- Paralogous protein(s): yqiW
Extended information on the protein
- Kinetic information:
- Domains: contains an CxC redox motif [3]
- Modification:
- S-bacillithiolation upon hypochlorite stress on Cys-53 PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- UniProt: P54170
- KEGG entry: [4]
- E.C. number:
Additional information
Expression and regulation
- Operon: yphP (according to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
YpdA, YqiW, YphP and YtxJ cooccur in those species predicted to synthesize bacillithiol.
References
