Difference between revisions of "PrsA"
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 876 bp, 292 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 876 bp, 292 aa | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yhaL]]'', ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yhaL]]'', ''[[sscA]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12835]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12835]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | ||
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=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| − | |||
=The protein= | =The protein= | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' dimeric or oligomeric protein {{PubMed|20487272}} | + | * '''[[SubtInteract|Interactions]]:''' dimeric or oligomeric protein {{PubMed|20487272}} |
* '''Localization:''' membrane associated {{PubMed|18763711,20487272}}, distinct spots organized in a helical pattern along the cell membrane {{PubMed|20487272}} | * '''Localization:''' membrane associated {{PubMed|18763711,20487272}}, distinct spots organized in a helical pattern along the cell membrane {{PubMed|20487272}} | ||
Revision as of 16:37, 1 July 2011
- Description: post-translocational folding of exported proteins (post-translocation molecular chaperone)
| Gene name | prsA |
| Synonyms | |
| Essential | yes PubMed |
| Product | post-translocation molecular chaperone |
| Function | protein folding |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 32 kDa, 9.122 |
| Gene length, protein length | 876 bp, 292 aa |
| Immediate neighbours | yhaL, sscA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
protein secretion, essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU09950
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: catalyses the post-translocational folding of exported proteins PubMed, required for folding of penicillin-binding proteins (PbpA, PbpB, PbpC, PbpD) PubMed
- Protein family: PpiC domain (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions: dimeric or oligomeric protein PubMed
- Localization: membrane associated PubMed, distinct spots organized in a helical pattern along the cell membrane PubMed
Database entries
- Structure: 1ZK6
- UniProt: P24327
- KEGG entry: [2]
- E.C. number: 5.2.1.8
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
