Difference between revisions of "NagB"
| Line 20: | Line 20: | ||
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 726 bp, 242 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 726 bp, 242 aa | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nagA]]'', ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nagA]]'', ''[[nagR]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15507]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15507]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | ||
| Line 38: | Line 38: | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | {{SubtiWiki regulon|[[ | + | {{SubtiWiki regulon|[[NagR regulon]]}} |
=The gene= | =The gene= | ||
| Line 55: | Line 55: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| Line 98: | Line 96: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | + | * '''Operon:''' ''[[nagA]]-[[nagB]]-[[nagR]]'' {{PubMed|21602348}} | |
| − | * '''Operon:''' | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** induced in the presence of N-acetylglucosamine ([[NagR]]) {{PubMed|21602348}} | ||
| + | |||
| + | * '''Regulatory mechanism:''' | ||
| + | ** [[NagR]]: transcription repression {{PubMed|21602348}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| Line 128: | Line 129: | ||
=References= | =References= | ||
| − | + | '''Additional publications:''' {{PubMed|21602348}} | |
<pubmed>6174502,15755726 </pubmed> | <pubmed>6174502,15755726 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:19, 24 May 2011
- Description: glucosamine-6-phosphate deaminase
| Gene name | nagB |
| Synonyms | |
| Essential | no |
| Product | glucosamine-6-phosphate deaminase |
| Function | N-acetylglucosamine utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism, Murein recycling | |
| MW, pI | 26 kDa, 5.717 |
| Gene length, protein length | 726 bp, 242 aa |
| Immediate neighbours | nagA, nagR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
cell wall degradation/ turnover, utilization of specific carbon sources
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35020
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: D-glucosamine 6-phosphate + H2O = D-fructose 6-phosphate + NH3 (according to Swiss-Prot)
- Protein family: NagB subfamily (according to Swiss-Prot)
- Paralogous protein(s): GamA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- UniProt: O35000
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
