Difference between revisions of "RapH"
| Line 66: | Line 66: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' binds to and thereby inhibits [[ComA]] activity {{PubMed|17581123}} | + | * '''Catalyzed reaction/ biological activity:''' |
| + | ** binds to and thereby inhibits [[ComA]] activity {{PubMed|17581123}} | ||
| + | ** RapH dephosphorylates [[Spo0F]]-P and thereby controls the [[phosphorelay]] {{PubMed|17581123}} | ||
| + | ** in addition to dephosphorylating [[Spo0F]], RapH can antagonize sporulation by sterically blocking phosphoryl transfer to and from [[Spo0F]] {{PubMed|21346797}} | ||
* '''Protein family:''' RAP family (according to Swiss-Prot) | * '''Protein family:''' RAP family (according to Swiss-Prot) | ||
| Line 90: | Line 93: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=3Q15 3Q15] ([[RapH]]-[[Spo0F]] complex) {{PubMed|21346797}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P40771 P40771] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P40771 P40771] | ||
| Line 136: | Line 139: | ||
=References= | =References= | ||
| − | <pubmed>16553878,20817675,17581123, 11948146, 11918817 </pubmed> | + | <pubmed>16553878,20817675,17581123, 11948146, 11918817 21346797 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 15:14, 25 February 2011
- Description: response regulator aspartate phosphatase, dephosphorylates Spo0F-P, control of the phosphorelay, control of ComA activity
| Gene name | rapH |
| Synonyms | yeeH, yzqA |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of sporulation initiation and ComA activity |
| Function and regulation of this protein in SubtiPathways: Phosphorelay | |
| MW, pI | 49 kDa, 6.121 |
| Gene length, protein length | 1293 bp, 431 aa |
| Immediate neighbours | yeeG, yeeI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
protein modification, transcription factors and their control, phosphorelay, quorum sensing
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU06830
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- UniProt: P40771
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: rapH PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
