Difference between revisions of "SftA"
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' aids in moving DNA away from the closing septum, binds DNA, DNA-dependent ATPase activity {{PubMed|19818024}} | + | * '''Catalyzed reaction/ biological activity:''' |
| + | ** aids in moving DNA away from the closing septum, binds DNA, DNA-dependent ATPase activity {{PubMed|19818024}} | ||
| + | ** the two DNA translocases [[SftA]] and [[SpoIIIE]] synergistically affect chromosome dimer resolution presumably by positioning the dif sites in close proximity, before or after completion of cell division, respectively {{PubMed|21239579}} | ||
* '''Protein family:''' | * '''Protein family:''' | ||
| Line 126: | Line 128: | ||
=References= | =References= | ||
| − | <pubmed>16479537 19788545 19818024 </pubmed> | + | <pubmed>16479537 19788545 19818024 21239579</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:35, 19 January 2011
- Description: DNA translocase
| Gene name | sftA |
| Synonyms | ytpS, cdtA |
| Essential | no |
| Product | DNA translocase |
| Function | resolution of chromosome dimers |
| MW, pI | 30 kDa, 9.955 |
| Gene length, protein length | 792 bp, 264 aa |
| Immediate neighbours | murC, ytpR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29805
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- aids in moving DNA away from the closing septum, binds DNA, DNA-dependent ATPase activity PubMed
- the two DNA translocases SftA and SpoIIIE synergistically affect chromosome dimer resolution presumably by positioning the dif sites in close proximity, before or after completion of cell division, respectively PubMed
- Protein family:
- Paralogous protein(s): SpoIIIE
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions: forms a hexamer PubMed
- Localization: Cytoplasm (Homogeneous) PubMed, co-localizes with FtsZ at nascent division sites PubMed
Database entries
- Structure:
- UniProt: C0SP86
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
